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Friday, June 7


Clinical Transplantation and Cord Blood Banking


Session IIIA

8:00 – 9:40 AM

Cord Blood Hematopoietic Stem Cell Transplantation: Indications, Results, and Cord Blood Unit Selection

Chairs: Vanderson Rocha & Michael Verneris

8:00 – 8:25 AM Refining the Indications for Cord Blood Transplantation

Daniel J. Weisdorf, MD, University of Minnesota
8:25 – 8:50 AM Cord Blood Transplantation for Malignant Disorders – Eurocord Results

Vanderson Rocha, MD, PhD, Oxford University
8:50 – 9:15 AM Cord Blood Transplantation for Benign Disorders

Joanne Kurtzberg, MD, Duke University
9:15 – 9:40 AM High Resolution Typing for A, B, C, DR1 in Single-Unit Cord Blood Hematopoietic Stem Cell Transplantation

Mary Eapen, MD, MS, Medical College of Wisconsin

9:40 – 10:00 AM

COFFEE BREAK - PACIFIC CONCOURSE


Session IIIB

10:00 AM – 12:00 PM

Cord Blood Unit Selection

Chairs: Vanderson Rocha & Michael Verneris

10:00 – 10:15 AM Selected Abstract Presentation - Improved Virus-Specific Immune Reconstitution After Cord Blood Transplantation Using Cord Blood-Derived Virus-Specific T-cells

Caridad Martinez, MD, Baylor College of Medicine
10:15 – 10:40 AM Pros and Cons Regarding the Use of NIMA and IPA: Significance, Practicalities, and Cost

Andromachi Scaradavou, MD, Memorial Sloan-Kettering Cancer Center & New York Blood Center National Cord Blood Program
10:40 – 11:10 AM Anti-HLA Antibodies and Outcomes after Cord Blood Transplantation

Annalisa Ruggeri, MD, Eurocord International Registry
11:10 – 11:30 AM The Significance of the Direction of the HLA Mismatch in Cord Blood Matching and the Implication of Graft-Specific Anti-HLA Antibodies

Marcelo Fernandez-Vina, PhD, Stanford University School of Medicine
11:30 – 12:00 PMPanel Discussion - Weisdorf, Rocha, Kurtzberg, Eapen, Scaradavou, Ruggeri, Fernandez-Vina
12:00 – 1:00 PM

LUNCH - PACIFIC CONCOURSE


Session IV

1:00 – 2:50 PM

New Data Regarding Double-Unit Cord Blood Transplantation

Chairs: Juliet Barker & Michael Verneris

1:00 - 1:20 PM Allele Level HLA Matching on Outcomes After Double-Unit Cord Blood Transplantation for Hematological Malignancies: Stronger Graft vs. Leukemia with HLA Mismatch

Claudio Brunstein, MD, PhD, University of Minnesota
1:20 - 1:50 PM REVIEW: Double-Unit Cord Blood Transplantation for Acute Leukemia

Juliet Barker, MBBS, Memorial Sloan-Kettering Cancer Center
1:50 - 2:10 PM Increased Relapse Associated with Mixed Donor-Donor Chimerism Following Double-Unit Cord blood Transplantation

Michael Verneris, MD, University of Minnesota
2:10 - 2:30 PM Outcomes of Double-Unit Cord Blood Transplantation for Adults with Mailgnant Disorders: Eurocord Registry Analysis

Vanderson Rocha, MD, PhD, Oxford University
2:30 - 2:50 PM Panel Discussion - Barker, Verneris, Brunstein, Rocha
2:50 – 3:10 PM

COFFEE BREAK - PACIFIC CONCOURSE


Session V

3:10 – 5:00 PM

Providing an Adequate Cell Dose for Adults Using Single-Unit Cord Blood

Chairs: Colleen Delaney, Mi Kwon, & Koen Van Besien

3:10 – 3:40 PM Cord Blood Transplantation Supported by Third-Party Donor Cells: Rationale, Results and Applications

Koen Van Besien, MD, PhD, Weill-Cornell Medical College
3:40 – 4:10 PM Single-Unit Cord Blood Combined with HLA-Mismatched Third-Party Donor Cells: Comparable Results to Matched Unrelated Donor Transplantation in High-Risk Patients with Hematologic Disorders

Mi Kwon, MD, Hospital General Universitario Gregorio Marañón
4:10 – 4:30 PM Cord Blood Transplantation Using Cells Expanded In Vitro

Colleen Delaney, MD, Fred Hutchinson Cancer Research Center
4:30 – 5:00 PMPanel Discussion: Are Double-Unit Cord Blood Transplants the Optimal Means of Providing an Adequate Cell Dose or Should Therapy be Supplanted by Cord Blood HCT Using Cells Expanded In Vitro or Cord Blood Transplants Supported by Third Party Cells?

Discussants - Delaney, Kwon, Van Besien

5:00 PM

ADJOURN


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