International Cord Blood Symposium Scientific Program


Wednesday, June 8, 2016

Noon – 7:00 p.m.
Registration Open

Thursday, June 9, 2016

6:30 a.m. – 5:30 p.m.
Registration Open

7:00 a.m. – 5:00 p.m.
Speaker Ready Room Open

7:30 a.m. – 8:00 a.m.
Breakfast in Exhibit Hall

Opening Plenary Session
8:00 a.m. – 10:00 a.m.

8:10 a.m. – 8:30 a.m.
CIRM 2.0 Building a Better Stem Cell Agency
C. Randal Mills, PhD, President & CEO
California Institute for Regenerative Medicine (CIRM)

Plenary Session
Challenges Faced by the U.S. Public Cord Blood Banking Industry
Chair: Brian Freed, PhD, DABHI, Executive Director
ClinImmune Labs

8:30 a.m. – 9:00 a.m.
Impact of BLA/IND Requirements on Public Cord Blood Banks
Brian Freed, PhD, DABHI, Executive Director
ClinImmune Labs

9:00 a.m. – 9:30 a.m.
FDA Perspectives on Continuing Requirements for BLA for CB
Speaker TBD

9:30 a.m. – 10:00 a.m.
NCBI Units: Is it Time to Revisit the Collection Criteria?
Merry Duffy, Director, Cord Blood, Biorepository, and Affiliated Services
National Marrow Donor Program

10:00 a.m. – 10:30 a.m.
Refreshment Break

Concurrent Workshops
10:30 a.m. – Noon

UCB Transplantation Workshop: Selection of CB Units in 2016

Chair: Claudio Brunstein, MD, PhD, Associate Professor, Department of Medicine Blood and Marrow Transplant Program
University of Minnesota

Session Description: TBD


The Spanish Experience
Jaime Sanz Caballer, MD, Hematologist
University Hospital La Fe, Spain
Session Description: TBD


The Japanese Perspective
Jun Ooi, MD, Associate Professor Department of Hematology/Oncology
Teikyo University School of Medicine
Session Description: TBD


Selection of Units for Expansion
Rebecca Haley, MD MT(ASCP)SBB, Medical Director
Cord Blood Bank Bloodworks Northwest
Session Description: TBD

Public CBB Inventory Considerations and Challenges Workshop

Chair: Donna Regan, MT(ASCP)SBB, Director
St. Louis Cord Blood Bank & Cellular Therapy Laboratory

Session Description: This workshop will address inventory challenges such as assessment of risk on assigning product disposition and how product designations affect perception of quality. Panelists will lead interactive discussions about how current practices – manufacturing, documentation and testing – impact sustainability today and maintain relevance into tomorrow.

Panel:
Sharon Miller, MT (ASCP), CHS(ABHI), Director of Regulatory Affairs
Clinimmune Labs–UCCBB
Tina Krieg, Quality Systems Specialist,
Bloodworks Northwest
Amanda Parrish, PhD, RAC, Director, Regulatory Affairs and Quality
Duke Translational Medicine Institute

Noon – 1:15 p.m.
Lunch in the Exhibit Hall

Plenary Session
1:15 p.m. – 3:00 p.m.

Plenary Session
Outcomes of Allogeneic CB Transplantation
Chair: Mark Walters, MD, Director, Blood and Marrow Transplantation (BMT) Program
Division of Hematology/Oncology
UCSF Benioff Children's Hospital Oakland

1:15 p.m. – 1:50 p.m.
Outcomes of CB Transplants from HLA Matched Sibling Donors – An Update
Mark Walters, MD, Director, Blood and Marrow Transplantation (BMT) Program
Division of Hematology/Oncology
UCSF Benioff Children's Hospital Oakland

1:50 p.m. – 2:25 p.m.
Impact of Residual Disease on Outcomes of CBT
Filippo Milano, MD, PhD, Assistant Member, Associate Director, Cord Blood Transplant Program
Fred Hutchinson Cancer Research Center

2:25 p.m. – 3:00 p.m.
Gut Microbiota and Outcomes After CBT
Robert Jenq, MD, Medical Oncologist
Memorial Sloan Kettering Cancer Center

3:00 p.m. – 3:30 p.m.
Refreshment Break

Concurrent Workshops
3:30 p.m. – 5:00 p.m.

Potency Assays for Cord Blood Units: What Do Banks Do? What Do Transplant Centers Look For?

Chair: Rebecca Haley, MD MT(ASCP)SBB, Medical Director
Cord Blood Bank Bloodworks Northwest

Session Description: This interactive session will begin with short cord blood bank presentations on their potency measures. Transplant centers representatives will follow with what they look for and value from these assays and how they use the results. A panel discussion including questions from the audience concerning test methods, their significance and usefulness, will follow.

Panel:
Rebecca Haley, MD MT(ASCP)SBB, Medical Director
Cord Blood Bank Bloodworks Northwest
Kristin Page, MD, Assistant Professor of Pediatrics
Duke University School of Medicine
Brian Freed, PhD, DABHI, Executive Director
ClinImmune Labs
Andromachi Scaradavou, MD, Pediatric Hematologic Oncologist
Memorial Sloan Kettering Cancer Center
Medical Director, National Cord Blood Program
New York Blood Center

"Standards and Regulations in Cell Therapy" Workshop

Chair: Naynesh Kamani, MD, Vice President, Center for Cellular Therapies and Research
AABB

Session Description: TBD


Regulation of Devices for UCB Processing
Speaker TBD
Session Description: TBD


NIST’s Role in Cell and Gene Therapy Manufacturing
Anne Plant, PhD, Division Chief, Biosystems and Biomaterials Division, Materials Measurement Laboratory
National Institutes of Standards and Technology
Session Description: TBD


Challenges and Solutions for Large Scale Manufacturing of Therapeutic Cells
Speaker TBD
Session Description: TBD

5:00 p.m. – 6:30 p.m.
Networking and Poster Reception in the Exhibit Hall

Friday, June 10, 2016

6:30 a.m. – 5:00 p.m.
Registration Open

7:00 a.m. – 5:00 p.m.
Speaker Ready Room Open

7:45 a.m. – 8:15 a.m.
Breakfast in Exhibit Hall

Plenary Session
8:15 a.m. – 10:00 a.m.

Plenary Session
CB Expansion Technologies – What is New?
Chair: Colleen Delaney, MD, MSc, Director, Program in Cord Blood Transplantation
Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance

8:15 a.m. – 8:50 a.m.
Results of Nicord Phase I–II Trials and Plans for Phase III Trial
Mitchell Horwitz, MD, Associate Professor of Medicine
Duke University School of Medicine

8:50 a.m. – 9:25 a.m.
Off the Shelf Expanded CB Units for Chemotherapy–Induced Neutropenia
Colleen Delaney, MD, MSc, Director, Program in Cord Blood Transplantation
Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance

9:25 a.m. – 10:00 a.m.
Cord Blood Expansion Using Pyrimidoindole Derivatives
Silvy Lachance, PhD, FRCP, Director, Fellowship Program in Stem Cell Transplantation, Associate Professor of Medicine, Clinical Researcher; Director, Medical and Administrative
Rosemont Hospital Université de Montréal

10:00 a.m. – 10:30 a.m.
Refreshment Break

Workshop
10:30 a.m. – Noon

Session Description: This will be presented in a "Speed Dating" round table format with assorted topics.

Optimizing Approaches to Public and Family Cord Blood Banking; Preparing for The Future
Chair: Joanne Kurtzberg, MD, Director, Carolinas Cord Blood Bank; Chief Scientific Officer, Robertson Clinical and Translational Cell Therapy Program; Director,Pediatric Blood & Marrow Transplant Program

Noon – 1:15 p.m.
Lunch in the Exhibit Hall

Joint AABB/Perinatal Stem Cell Society Plenary Session
1:15 p.m. – 3:00 p.m.

Review of Potential Clinical Uses of Perinatal Cells and Cord Tissue Derived Cells
Chair: Morey Kraus, Chief Scientific Officer of the Diagnostics Division
PerkinElmer, Inc.

1:15 p.m. – 1:50 p.m.
Human Placenta–Derived Adherent Cells: Biology and Therapeutic Potential
Robert Hariri, MD, PhD, Co–Founder, President
Human Longevity Cellular Therapeutics

1:50 p.m. – 2:25 p.m.
Role of Cord Derived CD 105 Positive MSC in Cardiac Repair
Joshua Hare, MD, Founding Director
Interdisciplinary Stem Cell Institute

2:25 p.m. – 3:00 p.m.
Heterogeneous Populations of Perinatal Stem Cells from Cord Tissue and Their Potential Use in Newborns with Hypoxic Ischemic Injuries
Morey Kraus, Chief Scientific Officer of the Diagnostics Division
PerkinElmer, Inc.

3:00 p.m. – 3:30 p.m.
Refreshment Break

Concurrent Workshops
3:30 p.m. – 5:00 p.m.

Isolation and Cryopreservation of Cord Related Tissue
Chair: Aby J. Mathew, PhD, Senior Vice President & Chief Technology Officer
BioLife Solutions, Inc.
Session Description: TBD


Cryopreservation of Cord Tissue
Kate Brown, PhD, Principal Scientist, Cord Blood Registry
Session Description: TBD


Cord and Amnion Processing Methods for Cyopreservation
Rouzbeh Taghizadeh, PhD, Director, and Founder
Perinatal Stem Cell Society Cofounder and Chief Scientific Officer,
Auxocell Laboratories, Inc.
Session Description: TBD


Processing of Amniotic Cells or Placental Cells
Sean Murphy, PhD, Assistant Professor,
Wake Forest Institute for Regenerative Medicine
Session Description: TBD

Regenerative Medicine Applications of UCB: Results of Preclinical Studies
Chair: Mervin C. Yoder, MD, Distinguished Professor,
Indiana University
Session Description: TBD


Human Umbilical Cord Blood Cells in Alzheimer's Disease–Like Murine Model
Speaker TBD
Session Description: TBD


A Cord Blood Monocyte–Derived Cell Therapy Product Accelerates Brain Remyelination
Speaker: Arjun Saha, PhD, Project Leader
Robertson Clinical and Translational Cell Therapy Program,
Duke University Medical Center
Session Description: TBD


Cord Blood Derived Endothelial Colony-Forming Cells for Regenerative Medicine Applications
Mervin C. Yoder, MD, Distinguished Professor,
Indiana University
Session Description: TBD


Saturday June 11, 2016

6:30 a.m. – 5:00 p.m.
Registration Open

7:00 a.m. – 3:00 p.m.
Speaker Ready Room Open

7:45 a.m. – 8:15 a.m.
Breakfast in Exhibit Hall

Plenary Session
8:15 a.m. – 10:00 a.m.

Plenary Session
Regenerative Medicine Applications of UCB in the Clinic: Results of Current Clinical Trials
Chair: Joanne Kurtzberg, MD, Director, Carolinas Cord Blood Bank; Chief Scientific Officer
Robertson Clinical and Translational Cell Therapy Program, Director, Pediatric Blood & Marrow Transplant Program

8:15 a.m. – 8:50 a.m.
Phase I Trial of autologous CB Cells in Young Children with Autism Spectrum Disorders
Geraldine Dawson, PhD, Professor, Departments of Psychiatry and Behavioral Sciences, Pediatrics, and Psychology and Neuroscience and Director
Duke Center for Autism and Brain Development

8:50 a.m. – 9:25 a.m.
Results of a Randomized Trial of CB Infusions in Cerebral Palsy
MinYoung Kim, MD, PhD, Professor & Director, Department of Rehabilitation Medicine, Director, Rehabilitation & Regeneration Research Center, Director, International Health Care Center
CHA Bundang Medical Center, CHA University, Seongnam, Korea

9:25 a.m. – 10:00 a.m.
A Randomized Study of Autologous Umbilical Cord Blood Reinfusion in Children with Cerebral Palsy
Joanne Kurtzberg, MD, Director, Carolinas Cord Blood Bank; Chief Scientific Officer, Robertson Clinical and Translational Cell Therapy Program, Director
Pediatric Blood & Marrow Transplant Program

10:00 a.m. – 10:30 a.m.
Refreshment Break

Plenary Session
10:30 a.m. – Noon

Best Oral Abstract Presentations

Chair: Heather Brown, MS, CGC, Vice President, Scientific and Medical Affairs

Noon – 1:15 p.m.
Lunch in the Exhibit Hall

Workshop
1:15 p.m. – 3:00 p.m.

Review of Best Practices for Cord Blood Collection
This session offers the perfect opportunity for Obstetricians and nurses to understand the latest advances in cord blood collection. The discussion includes why an OB provider should collect cord blood, explores different collection models and their success rates as well as addresses training and maximizing collection volumes. The session will wrap up with a presentation on current and future applications of cord blood therapies.
Chair: Joanie Y. Hare, MD

Overview: Why Should an OB Provider Collect Cord Blood?
Speaker Joanie Y. Hare, MD

Models for Cord Blood Collection
Speaker TBD

Training for Cord Blood Collection
Del Steckler, RN, BSN, MMA, Be The Match Cord Blood Recruitment Manager
National Marrow Donor Program

Maximizing Cord Blood Collection Volumes
Speaker: TBD

Current and Future Applications of CB Therapies
Joanne Kurtzberg, MD, Director, Carolinas Cord Blood Bank; Chief Scientific Officer, Robertson Clinical and Translational Cell Therapy Program, Director
Pediatric Blood & Marrow Transplant Program

3:30 p.m.
Closing and Adjournment

Held collaboratively between AABB and CBA

Support provided by