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Thursday, May 18, 2006
| 6:00 - 8:00 PM |
Complimentary Wine and Cheese Reception for all Attendees and Exhibitors. (The registration desk will be open 2PM to 8PM) |
Friday, May 19, 2006
| 7:00 - 8:00 AM |
BREAKFAST(provided) Exhibits Open (On site registration available) |
| Session I. 8:00 AM - Noon The state of the art in cord blood transplantation |
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Chairpersons: John Wagner, M.D. and Vanderson Rocha, M.D., Ph.D. |
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Session IA: |
8:00 - 8:40 AM |
Review Lecture: Umbilical cord blood transplantation: The state of the art. John Wagner, M.D., University of Minnesota, Minneapolis, MN |
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Session IB: |
Reduced-Intensity Pre-Transplantation Conditioning Regimens |
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8:40 - 9:00 AM |
Reduced-intensity conditioning regimen for unrelated cord blood transplantation in adults. Vanderson Rocha, M.D., Ph.D., Hospital Saint-Louis, Paris, France |
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9:00 - 9:20 AM |
Reduced-intensity unrelated cord blood transplantation for patients with hematologic malignancies. Shigesaburo Miyakoshi, M.D., Toranomon Hospital, Tokyo, Japan |
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9:20 - 9:40 AM |
Reduced-intensity allogeneic cord blood hematopoetic cell transplantation in pediatric patients with malignant and non-malignant diseases. Prakash Satwani, M.D., Columbia University, New York, NY |
| 9:40 - 10:00 AM |
COFFEE BREAK - Exhibits Open |
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Session IC: |
10:00 - 10:30 AM |
Review Lecture: Double umbilical cord transplants (UCBT) with myeloablative or reduced intensity conditioning regimens. K. Scott Baker, M.D., University of Minnesota, Minneapolis, MN |
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Session ID: |
Double cord blood transplants |
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10:30 - 10:50 AM |
Disease-free survival after double cord blood transplantation using a reduced intensity chemotherapy only conditioning regimen. Karen Ballen, M.D., Massachusetts General Hospital, Boston, MA |
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10:50 - 11:10 AM |
Risk of relapse after umbilical cord blood transplantation in patients with acute leukemia: marked reduction in recipients of two units. Michael Verneris, M.D., University of Minnesota, Minneapolis, MN |
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11:10 - 11:30 AM |
Myeloablative single cord transplants versus dual cord transplants in adults with acute leukemia. Michael Creer, M.D., St. Louis Cord Blood Bank, St. Louis, MO |
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11:30 AM - Noon |
Panel discussion with questions and comments from the audience.
Moderators: John Wagner and Vanderson Rocha
Panel: Shigesaburo Miyakoshi, Prakash Satwani, K. Scott Baker, Michael Verneris, Michael Creer |
| Noon - 1:00 PM |
LUNCH (provided) - Exhibits Open |
| Session II. 1:00 - 2:20 PM |
Optimal selection of stem cell products for hematopoietic cell transplantation |
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Chairpersons: Dennis Confer, M.D., and Juliet Barker, M.B.B.S. |
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1:00 - 1:10 PM |
HLA Matching for Transplantation: Lessons from Bone Marrow. Dennis Confer, M.D., National Marrow Donor Program, Minneapolis, MN |
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1:10 - 1:20 PM |
Analysis of 608 umbilical cord blood (UCB) transplants: HLA-match is a critical determinant of transplant-related mortality (TRM) in the post-engraftment period even in the absence of acute graft-vs-host disease (aGVHD). Juliet Barker, M.B.B.S., Memorial Sloane-Kettering Cancer Center, NY |
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1:20 - 1:30 PM |
Allogeneic hematopoietic stem cell transplantation (HSCT) in the treatment of acute lymphocytic leukemia (ALL) in 126 adults: Impact of donor source on leukemia-free survival (LFS). Priya Kumar, M.D., University of Minnesota, Minneapolis, MN |
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1:30 - 1:40 PM |
A study of the impact of number and type of HLA incompatibilities and cell dose on outcomes of unrelated cord blood transplants for patients with malignant and non malignant sources. Eliane Gluckman, M.D., Hospital Saint-Louis, Paris, France |
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1:40 - 2:20 PM |
Panel discussion - Development of a consensus statement on the optimal selection criteria for cord blood stem cell products.
Moderator: Dennis Confer
Panel: Juliet Barker, Eliane Gluckman, Joanne Kurtzberg, John Wagner |
| 2:20 - 2:40 PM |
COFFEE BREAK - Exhibits Open |
| Session III. 2:40 - 4:00 PM |
Umbilical cord blood transplantation for patients with transfusion-dependent thalassemia and sickle cell anemia |
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Chairpersons: Joseph Rosenthal, M.D. and Mary Eapen, M.D., M.S. |
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2:40 - 3:00 PM |
Review Lecture: Umbilical cord blood transplantation for transfusion-dependent thalassemia and sickle cell disease. Mark Walters, M.D. Children's Hospital Oakland Research Institute, Oakland, CA |
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3:00 - 3:20 PM |
Unrelated cord blood transplantation for hemoglobinopathies. Tang-Her Jaing, M.D., Chang Gung Children's Hospital, Taoyuan, Taiwan |
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3:20 - 3:40 PM |
Reduced intensity conditioning in stem cell transplantation for non-malignant disorders. Shalini Shenoy, M.D., Washington University Medical Center, St. Louis, MO |
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3:40 - 4:00 PM |
Panel discussion with questions and comments from audience
Moderators: Joseph Rosenthal and Mary Eapen
Panel: Mark Walters, Tang-Her Jaing, Shalini Shenoy |
| 4:00 PM |
ADJOURNMENT
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Saturday, May 20, 2006
| 7:00 - 8:00 AM |
BREAKFAST(provided) Exhibits Open (Registration desk open for single day registrations) |
| Session IV. 8:00 - 10:00 AM Quality issues in cord blood transplantation |
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Chairpersons: Emer Clarke, Ph.D. and Michael Creer, M.D. |
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8:00 - 8:30 AM |
Review Lecture: A report from the NMDP research committee on evaluating the quality of cord blood units. Emer Clarke, Ph.D., Stem Cell Technologies, Vancouver, BC, Canada |
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8:30 - 8:50 AM |
An empirical analysis of the probability of finding a well-matched cord blood unit with adequate cell dose. Cladd Stevens, M.D., New York Blood Center, NY |
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8:50 - 9:10 AM |
Transplantation outcome of plasma depleted cord blood units and the effect of post-thaw washing. Robert Chow, M.D., StemCyte International Cord Blood Center, Arcadia, CA |
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9:10 - 9:30 AM |
Comparison of cord blood product thawing methods on cell recovery and progenitor integrity. Michael Creer, M.D., St. Louis Cord Blood Bank, St. Louis, MO |
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9:30 - 10:00 AM |
Panel discussion with questions and comments from audience
Moderators: Emer Clarke and Michael Creer
Panel: Pablo Rubinstein, Robert Chow |
| 10:00 - 10:20 AM |
COFFEE BREAK - Exhibits Open |
| Session V. 10:20 AM - Noon |
Immune reconstitution following UCBT: Graft-versus- leukemia, infectious complications, and adoptive immunotherapy |
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Chairpersons: Kenneth Weinberg, M.D. and Laurence Cooper, M.D., Ph.D. |
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10:20 - 10:40 AM |
Review Lecture: Graft-versus-leukemia effect after allogeneic transplantation for acute leukemia. Mary Eapen, M.D., M.S., Center for International Blood and Marrow Transplant Research (CIBMTR), Milwaukee, WI |
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10:40 - 11:00 AM |
CMV infections after cord blood transplantation. Maria S. Albano, Ph.D, New York Blood Center, New York, NY |
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11:00 - 11:20 AM |
NK cells and KIR mismatch in cord blood transplantation. Jeffrey S. Miller, M.D., University of Minnesota, Minneapolis, MN |
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11:20 - 11:40 AM |
Optimal ex-vivo expansion of cord blood natural killer (NK) cells, NK cytotoxicity and NK receptor expression: Potential for CB adoptive cellular immunotherapy. Prakash Satwani, M.D., Columbia University, New York, NY |
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11:40 - Noon |
Differentiation of naïve cord blood T cells into CD19-specific cytolytic effectors for post-transplant adoptive immunotherapy. Laurence Cooper M.D., Ph.D., MD Anderson Cancer Center, Houston, TX |
| Noon - 1:00 PM |
LUNCH (provided) - Exhibits Open |
| Session VI. 1:00 - 2:20 PM Transplantation of children |
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Chairpersons: Paul Szabolcs, M.D. and Eliane Gluckman, M.D. |
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1:00 - 1:40 PM |
Review Lecture: Progress in cord blood transplantation for inborn errors of metabolism. Joanne Kurtzberg, M.D., Duke University, Durham, NC |
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1:40 - 2:00 PM |
Unrelated donor hematopoietic stem cell transplantation in children with acute leukemia: Risks and benefits of umbilical cord blood vs. bone marrow. Mary Eapen, M.D., M.S., Center for International Blood and Marrow Transplant Research (CIBMTR), Milwaukee, WI |
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2:00 - 2:20 PM |
Outcomes after unrelated cord blood transplantation in children with acute lymphoblastic leukemia: Eurocord-Netcord survey. Vanderson Rocha, M.D., Ph.D., Hospital Saint-Louis, Paris, France |
| Session VII. 2:20 - 2:50 PM |
A report from the Health Resources and Services Administration (HRSA): Implementing the Stem Cell Therapeutic and Research Act of 2005. Robert L. Baitty, M.P.P., Director, Blood Stem Cell Transplantation Program, Division of Transplantation, HRSA |
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Chairperson: Richard Champlin, M.D.
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| 2:50 - 3:10 PM |
COFFEE BREAK - Exhibits Open |
| Session VIII. 3:10 - 5:00 PM |
Cord blood cell biology, ex-vivo expansion, regenerative medicine |
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Chairpersons: Hal Broxmeyer, Ph.D. and Mary Laughlin, M.D. |
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3:10 - 3:40 PM |
Review Lecture: Ex-vivo expansion and homing of cord blood stem cells. Hal Broxmeyer, Ph.D., University of Indiana, Indianapolis, IN |
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3:40 - 4:00 PM |
Culture of CD34+ umbilical cord blood progenitors with Notch ligand results in enhanced and more rapid human engraftment in a preclinical NOD/SCID mouse model. Colleen Delaney, M.D., Fred Hutchinson Cancer Research Center, Seattle, WA |
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4:00 - 4:20 PM |
Umbilical cord blood derived CD133+ cells: Homing capability in vasculogenesis and immunogenicity. Mary Laughlin, M.D. Case Western Reserve University, Cleveland, OH |
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4:20 - 4:40 PM |
Isolation and characterization of umbilical cord blood-derived multipotent stem cells arising from adherent CD45+/CD34+ cell subset. Dan Collins, Ph.D., Chief Scientific Officer, BioE, Inc., St. Paul, MN |
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4:40 - 5:00 PM |
Immune reconstitution after umbilical cord blood transplantation. Paul Szabolcs, M.D., Duke University Medical Center, Durham, NC |
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