Scientific
Program
Scientific
Program

last updated:
May 26, 2005

click HERE for a printable PDF file of the program brochure

Presented by the
California Blood Bank Society
Supported by unrestricted educational grants from StemCyte, the National Marrow Donor Program and HRSA*

*The 3rd Annual International Umbilical Cord Blood Bank Transplantation Symposium was partially financially supported by a contract between the Health Resources and Services Administration, U.S. Department and Health and Human Services, and the California Blood Bank Society. Any opinions, findings, conclusions or recommendations expressed or presented at this conference are those of the presenters and do not necessarily reflect the views of the U.S. Government.


GOALS OF THE SYMPOSIUM:

  1. INCREASE AWARENESS AMONG TRANSPLANT PHYSICIANS AND OTHER MEDICAL PROFESSIONALS OF THE CLINICAL EFFECTIVENESS OF CORD BLOOD TRANSPLANTATION.

  2. ALLOW FOR EXCHANGE OF UP-TO-DATE BASIC AND CLINICAL DATA REGARDING CORD BLOOD TRANSPLANTATION AMONG LEADERS IN THE FIELD.

Thursday, June 2, 2005

6:00 – 8:00 P.M. Pre-Symposium Reception


A Complimentary Wine and Cheese Reception for all Attendees and Exhibitors.
(The registration desk will be open.)

Friday June 3, 2005

7:00 - 8:00 A.M. BREAKFAST
(provided)
Exhibits Open (On site registration available)

8:00 to 8:10 A.M.

Welcome and Acknowledgements

Session I. 8:10 A.M. - NOON

Umbilical Cord Blood Transplantation of Adults - Current Results and Future Directions.
Chairpersons: John Wagner, M.D. and Frederick Appelbaum, M.D.
(1)
8:10 - 8:40 A.M. A comparison of unrelated marrow vs. unrelated cord blood transplants in adults. Eliane Gluckman, M.D. Hospital Saint-Louis, Paris, France.
(2)
8:40 - 9:00 A.M. Cord blood transplants for acute leukemias in adults - The New York Blood Center experience. Pablo Rubenstein, M.D. New York Blood Center, New York, NY.
(3)
9:00 - 9:20 A.M. Cord blood transplants for adults using myeloablative conditioning. Satoshi Takahashi, M.D., University of Tokyo, Tokyo, Japan.
(4)
9:20 - 9:40 A.M. Non-myeloablative cord blood transplantation in adults. John Wagner, M.D., University of Minnesota, Minneapolis, MN.
(5)
9:40 - 10:00 A.M. Comparison of adult allogeneic umbilical cord blood transplantation between the myeloablative and non-myeloablative conditioning regimens. Haruko Tashiro, M.D., Teikyo University, Tokyo, Japan.
10:00 - 10:20 A.M. COFFEE BREAK

Exhibits Open

Umbilical Cord Blood Transplantation of Adults - Current Results and Future Directions (continued).
(6)
10:20 - 10:40 A.M. Cord blood transplants for indolent lymphoid malignancies in adults. Juliet Barker, M.D., University of Minnesota, Minneapolis, MN.
(7)
10:40 - 11:10 A.M. Double cord blood transplants. John Wagner, M.D., University of Minnesota, Minneapolis, MN.
(8)
11:10 - 11:30 A.M. Unrelated single cord blood transplants supported by co-infusion of a low number of mobilized peripheral blood highly purified CD34+ cells from a third party donor after low toxicity myeloablative conditioning. Manuel N. Fernandez, M.D., Hospital Puerta de Hierro, Madrid, Spain.
11:30 - NOON Panel Discussion with Questions/Comments from Audience: Cord Blood Transplantation in Adults.

Moderators: John Wagner and Frederick Appelbaum

Noon - 1:00 P.M. LUNCH
(provided)
Exhibits Open


Session II. 1:00 - 2:00 P.M.

Infectious Disease Complications and Immune Reconstitution after Cord Blood Transplantation.
Chairperson: Richard Champlin, M.D.
(1)
1:00 - 1:20 P.M. Infectious complications following unrelated cord blood transplantation. Jo-Anne van Burik, M.D., University of Minnesota, Minneapolis, MN.
(2)
1:20 - 1:40 P.M.

Incidence and risk factors of early severe infections after unrelated cord blood transplantation. Mary Laughlin, M.D., Case Western Reserve University, Cleveland, OH.

(3)
1:40 - 2:00 P.M. Immune reconstitution after umbilical cord blood transplantation. Nelson Chao, M.D., Duke University, Durham, NC.

2:00 - 2:15 P.M. COFFEE BREAK

Exhibits Open

Session III. 2:15 - 4:00 P.M.

Approaches to Augment the Efficacy of Umbilical Cord Blood Transplants.
Chairpersons: Hal Broxmeyer, Ph.D. and Larry Lasky, M.D.
(1)
2:15 - 2:35 P.M. T-Regulatory Cells. Bruce Blazar, M.D., University of Minnesota, Minneapolis, MN.
(2)
2:35 - 2:55 P.M. Transplantation of cord blood expanded ex vivo. Elizabeth J. Shpall, M.D., MD Anderson Cancer Center, Houston, TX.
(3)
2:55 - 3:15 P.M. Hematopoietic recovery after unrelated umbilical cord blood allogeneic transplantation in adults treated with in vivo stem cell factor and filgrastim administration. Mary Laughlin, M.D., Case Western Reserve University, Cleveland, OH.
(4)
3:15 - 3:35 P.M. An algorithm for selection of stem cell products for hematopoietic cell transplantation with comments about choosing the best umbilical cord blood unit. Juliet Barker, M.D., University of Minnesota, Minneapolis, MN.
(5)
3:35 - 4:00 P.M. Augmentation of homing of cord blood stem cells. Hal Broxmeyer, Ph.D., Indiana University School of Medicine, Indianopolis, IN.
4:00 - 4:30 P.M. Panel Discussion with Questions/Comments from Audience: Methods to Augment the Efficacy of Cord Blood Transplantation.

Moderators: Hal Broxmeyer and Larry Lasky
4:30 P.M. Adjourn

Saturday June 4, 2005

7:00 - 8:00 A.M. BREAKFAST
(provided)
Exhibits Open

Session IV. 8:00 - 10:00 A.M.

Collection, Processing, Banking, Thawing, and Administration of Cord Blood Units - Quality Issues.
Chairpersons: Jeffrey McCullough, M.D. and Dennis Confer, M.D.
A. 8:00 - 8:20 A.M. Standardization of cord blood banking procedures in the NMDP network. Joanne Kurtzberg, M.D., Duke University, Durham, NC.
B. 8:20 - 8:40 A.M. Issues in the quality of umbilical cord blood stem cells for transplantation. Jeffrey McCullough, M.D., University of Minnesota, Minneapolis, MN.
C. 8:40 - 9:30 A.M. Quality control of progenitor cell assays.
(1)
8:40 - 8:55 A.M. A comparison of pre- and post-cryopreservation CD34+ counts from cord blood units. Rafael Bornstein, M.D., Madrid Cord Blood Bank, Madrid, Spain.
(2)
8:55 - 9:15 A.M. Standardization of CFU assays. Emer Clarke, Ph.D, StemCell Technologies, Vancouver, BC, Canada
(3)
9:15 - 9:30 A.M. Post-thaw characterization of progenitor cell viability in cord blood products. Michael Creer, M.D., St. Louis Cord Blood Bank, St. Louis, MO.
9:30 - 10:00 A.M. Panel Discussion with Questions/Comments from Audience:
Quality Issues Regarding Cord Blood Units.

Moderators: Jeffrey McCullough and Dennis Confer

10:00 - 10:20 A.M. COFFEE BREAK

Exhibits Open

Session V. 10:20 A.M. - NOON Transplantation of Children/Genetic Disorders
Chairpersons: Joanne Kurtzberg, M.D. and Tang-Her Jaing, M.D.
(1)
10:20 - 10:50 A.M. Cord Blood Transplantation for children with genetic disorders - data from the COBLT study. Joanne Kurtzberg, M.D., Duke University, Durham, NC.
(2)
10:50 - 11:15 A.M. Unrelated cord blood transplantation for childhood hematologic malignancies. Eliane Gluckman, M.D., Hospital Saint-Louis, Paris, France.
(3)
11:15 - 11:30 A.M. Unrelated cord blood transplantation for transfusion-dependent thalassemia in young children. Tang-Her Jaing, M.D., Chang Gung Children's Hospital, Taoyuan, Taiwan.
(4)
11:30 - 11:45 A.M. Outcomes of unrelated cord blood transplants and allogeneic-related hematopoietic stem cell transplants in children with high-risk acute lymphocytic leukemia. David A. Jacobsohn, M.D., Northwestern University, Chicago, IL.
(5)
11:45 - NOON Total body irradiation, fludarabine, melphalan and allogeneic hematopoietic stem cell transplantation for advanced pediatric hematologic malignancies. Demetrios Petropoulos, M.D., MD Anderson Cancer Center, Houston, TX.
NOON - 1:00 P.M. LUNCH
(provided)
Exhibits Open

Session VI. 1:00 - 3:00 P.M. Multipotent Stem Cells and Regenerative Medicine.
Chairpersons: Catherine Verfaillie, M.D. and Joanne Kurtzberg, M.D.
(1)
1:00 - 1:30 P.M. Culture of multipotent adult progenitor cells (MAPCs). Catherine Verfaillie, M.D., University of Minnesota, Minneapolis, MN.
(2)
1:30 - 2:00 P.M. The biology of mesenchymal cells and their clinical application. Darwin Prockop, M.D., Tulane University, New Orleans, LA.
(3)
2:00 - 2:20 P.M. Wharton's jelly stem cells: isolation, extraction and preliminary characterization. Curtis Cetrulo, M.D., Tufts University School of Medicine, Boston, MA.
(4)
2:20 - 2:40 P.M. The fetal sheep model for assessing the full differentiative potential of human stem cells. Esmail D. Zanjani, Ph.D. University of Nevada, Reno, NV.
2:40 - 3:00 P.M. Panel Discussion with Questions/Comments from Audience: Multipotent Stem Cells and Regenerative Medicine.

Moderators: Catherine Verfaillie and Joanne Kurtzberg
3:00 - 3:20 P.M. COFFEE BREAK

Exhibits Open

Session VII. 3:20 - 5:00 P.M. Accreditation Issues and the report from the Institute of Medicine.
Chairperson: Richard Champlin, M.D.
(1)
3:20 - 3:40 P.M. The FACT/NETCORD Accreditation Program. Phyllis Warkentin, M.D., University of Nebraska Medical Center, Omaha, NE.
(2)
3:40 - 4:00 P.M. AABB Standards and Accreditation - 2005. James McMannis, Ph.D., MD Anderson Cancer Center, Houston, TX.
(3)
4:00 - 4:30 P.M. The Institute of Medicine Report. Richard Champlin, M.D., MD Anderson Cancer Center, Houston, TX.
4:30 - 5:00 P.M. Panel Discussion with Questions/Comments from Audience: Comments on Accreditation Issues and the Institute of Medicine Report.

Moderator: Richard Champlin
5:00 P.M. Adjourn
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